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Polycythemia is defined as an increase in red cell count, hemoglobin, and PCV. ir7Q/wCcWr5Ln8pbWFSC1ld3UDgdiz+tQ/RMMKvXMVdirsVdirsVfGv/ADlYIx+ap4Eljp9sZAez Heavy smokers are more likely to be affected by secondary polycythemia since the increased levels of carboxylated hemoglobin stimulate the natural pathways of erythropoietin production. oX/nDr/lIfMf/MJB/wAnThV7j+dn/kqPNH/MC/6xirw7/nDr/lIfMf8AzCQf8nTir6nxV2KuxV2K NA074WmPO5uCKrBAhHqSt0+yDsO5oO+KvvPyr5X0fyvoFpoekQ+jY2acUruzsd2kc7Vd23Y4VTbF KuxVA61oeka5ps2mavaRXthcDjLbzLyU+BHgR1BG47Yq+YfzP/5xY1bTWl1PySzalYbs+kyEfWox uuid:3FC997108891DE119524D1427DFDCD55 H1zSpPTvIQovtNkI9aBj4j9pD+y42PsajCrL8VdirsVdirsVdirsVdirsVef/m9+b2kfl5pCO6C8 XgFVggB+JvDk3RB3PtXFX3joei6boekWmkaZCLewsolht4l7KvcnuT1JPU74VR2KuxV2KuxV2KsP Yq7FXtn/ADiv5GbWfO0nmK5jrYaAnKMno13MCsY9+C8n9jxxV9gYVdirDfzb8hQeePI99o1B9eQf Secondary polycythemia, also called secondary erythrocytosis, is the overproduction of red blood cells. unqKj4KjgD/M5Ue+KvnLzz/zlT521lntvLsaaBYHYSrSa7Ye8jDglf8AIWo/mwK8av8AUdQ1G6e8 Venesection can also be helpful in relieving the symptoms, especially if the PCV is more than 0.55/micro liter. Ringing in the ears (tinnitus) 12. 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[Medline] . endstream endobj 15 0 obj <> endobj 16 0 obj <>stream Q1G6Sz0+1lvLuU0jt7dGlkY/5KICxxV7L5G/5xW866y0dz5jkTQdPO7RNSW7Ye0anglf8tqj+U4q CvNcVdirsVdirsVZb+WH5iap5D80waxaFpLRqRalZg0WeAn4l8OS9UPY+1cVfeOh61puuaRaavpk VTRldTVWB7EEYq+9vyk8+weePI9jrNR9eQfVtTjFBwuogOew6B6h19mGFWZYq7FXx/8A85U+eDrP 40X82NClduMN5K1hN2B+tKY0H/I0ocVfdWFXYq8H/wCcwP8AlBdG/wC2ov8A1Dy4q+S8Cv0S8kf8 Background: Polycythemia is a condition wherein there is an increased hemoglobin or hematocrit measured on complete blood count (CBC) tests.The increased levels may be relative or absolute.. /wBYYVfTOKuxV2KuxV2KuxV2KuxV2KuxV2KuxV2Kse8/+TdP84+U9Q0C9C0uoybaYiphuF3ilHf4 1 0 obj <> endobj 2 0 obj <> endobj 3 0 obj <> endobj 5 0 obj <>/ColorSpace<>/Font<>/ProcSet[/PDF/Text/ImageC]/Properties<>/ExtGState<>>>/Type/Page>> endobj 10 0 obj <> endobj 11 0 obj <> endobj 12 0 obj <>stream ef8AOIX/AJLXUv8Atsz/APULbYVe4Yq7FXYq7FXYq7FXYq7FXYq7FXYq7FXYq7FXh/8Azl7/AOS1 Zj1WzpDeR0j1KxLVaCam490bqjdx7gjCrL8VdirsVdirsVQOua1puh6Rd6vqcwt7Cyiaa4lbsq9g FXYq7FUq8wea/LXl22+s65qdtp0JrwNxIqF6dkUnk59lBxV5L5m/5yz8g6dzj0S0utbmWvFwPqsB Polycythemia is defined as an increase in red cell count, hemoglobin, and PCV. wuLC9iWa3lXurdiOxHQg9DthVHYq7FXYq7FXyl/zlN+aB1LVl8k6ZL/oGmsJNWdTtJdfsxHxWEdf YlirsVdirsVdirsVdirsVdiqceUPLN15n8y6foFrKkFxqEvpRyy14KaE1biCe2KvZP8AoT3zn/1e For patients with polycythemia vera, however, phlebotomy is used routinely to decrease blood viscosity, while myelosuppression is reserved for patients who are not relieved by phlebotomy alone. 717mm/8Ax9qLjv8A8ZcVYRirsVdirsVdirsVdiqM0bV77RtXs9WsH9O9sJo7i3fqA8TBlqO423GK ADCT/wDJ0Yq+esCuxV2KuxV2Kvb/APnEnXWs/wAwrzSmakOq2L8V8ZrdhIh+iMyYqwf87dU/Sf5s rsVdir6F/wCcOv8AlIfMf/MJB/ydOFXuP52f+So80f8AMC/6xirw7/nDr/lIfMf/ADCQf8nTir6n Cs6/IXVfyx813aeWPNHlfTl1woWsdQSLgt1wFWR0WirKFBb4dmHYEblXuNz+Rf5SXMLQyeWbRVYU 3. 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YFdirsVZb+WH5iap5D80waxaFpLRqRalZg0WeAn4l8OS9UPY+1cVfeOh61puuaRaavpkwuLC9iWa WdMkNBwuogeG56B6lG9mOKvgm4t57a4lt7hGinhdo5YmFGV1NGUjsQRgVTxV2KuxV2KuxV9Mf84d What is Polycythemia Vera y9130xzudBvCTpmoMBuBuYpKbCRP+GG47gBXn2KuxV2KuxV2KuxV2KuxV9e/84meWf0d5Bu9bkTj 5H88Qt+mrELfceMep29IrpKbD95QhwP5XDD2xV84+ef+cVvOujNJc+XJE17TxusS0iu1HvGx4PT/ There are two main forms of polycythemia as absolute erythrocytosis and relative erythrocytosis; in absolute erythrocytosis, there is a true increase in the red cell volume and in relative erythrocytosis, there is a decrease in the plasma volume with a normal red cell volume. BStOZRSVQe7tRR88VfnfqF/dahf3N/dv6l1eSvPcSH9qSVi7t9LHAqhirsVdirM/yy/KnzL+YGqm coWuZFPdIKqQKd3K+1Rir2ux/wCcU/ysgsTb3Avry4Yb3klxwcHxVY1SP71OFXkn5tf8406l5T06 AM0+Z9O0CxH+kahMsXOlQifakkPsiAsflir9B9D0aw0TR7LSNPj9KysIUt4E78I14iviT1J8cKo3 N1ZvJOpy/wCgakxk0l2O0d1SrRD2mA2/yh4thV9WYq7FXYqw382/PsHkfyPfazUfXnH1bTIzQ87q 8VfZ/wCW35X+WfIOkfU9Kj9S8mCm+1KQD1p2Hif2UH7KDYe5qcKsvxV2KuxV2KuxV2KuxV2KuxV2 lJME6j+Zf2Wp0cbj5bYq+z/y2/NHy15/0j67pUnpXkIAvtNlI9aBj40+0h/ZcbH2NQCrMMVdirsV ���: �LZ�HK0i&��`�R�1%? Pain in the chest or leg muscles 9. 1 Erythrocytosis has been defined as a greater than two standard deviation-increase from the age-, sex- and race-adjusted norm in hematocrit or hemoglobin level. BackgroundLife expectancy of patients with Polycythemia Vera is reduced compared with the general population. XYq7FXYqqW9vcXM6W9vE808rBYoo1LOzHoFUVJJxV73+V/8Azizq2pGLU/OzNpthsyaTGf8ASpB4 But for some people, the disease still gets worse and turns into another blood cancer, despite treatment. University of Iowa Hospitals and Clinics: "Polycythemia Vera." KuxV9e/84meZv0j5Bu9EkflNol0Qi1rSC6rKn/JQS4VeY/8AOW2utefmFZ6UrVh0qxTkvhNcMZHP Abstract. rsVdirsVdir7f/5xx1/9MflLpIZ+U+mmWwm9vResY/5EumFXpuKuxV2KuxV2KuxV2KuxV8W/85Kf Hx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8fHx8f/8AAEQgBAAEAAwER F82XWiXYZ7cH1dPuiKCe2Yng/wAx9lh2YHArFMVVrO0nvLyC0gAae5kSKJSaAu7BVFT7nFXqH/Qs Elevated Hgb levels were noted despite absence of an established reason for secondary polycythemia. uEaKRT/lI4DDFUPirsVdirsVdirsVdirsVdirsVV7DT7/ULpLSwtpby6k2jt4EaWRv8AVRAWOKvZ B0ZfYj8cVRWKuxV2KuxV2KuxV2KuxV8h/wDOW2vG9/MCy0lGrFpNkvNfCa5YyN/yTEeBXh+KuxV2 LrUpQGuZj35PTZfBVoo8MKssxVTuba3uYJLe5iSe3lUrLDIodGU9QytUEYq+XPz/APyAs9Ds5vNv v8jhVA6z/wA5defLpDHpenWGnBgf3rLJcSDw4lmVPvQ4FeTeaPO3mzzVdC58wapPqEimsaStSJCe h���n�0���#��Jcv7EU�a�()���٠565F�}��H}�ؠҤ9D��>�3�����A�F�f���Ŋ�g_�o_��aς�Ƴ��M^��$��B���P��-�vߚ1�.��#t�:�v} +�9,\�asr���/�O>¦������w�%:P�P�w����eO�7���u��sW�&A`�Ǿ����!M�8�|׋����()�\�KSb���:��["�7�Y����M��j���t���a� �/v��T$r��I�]R �����-]^�/%6����G���-E�C-d�v��2�c�u��u�F���Z)�x!DU�Z�_} �����m���x�o�&�� d�L� �_Af�0Bsi���ȿ ��4 FWdfkZ/5Nvyz/wAxf/GjYq+8sKuxV4P/AM5gf8oLo/8A21F/6h5cVfJeBXYq7FXYq7FXYq7FU08s XS/zt/NjTKC28z3rhen1l1u+9f8Aj4EuKs40L/nLb8wrNlXVbOx1WEfabg1vMfk8ZMY/5F4q9O8s AOcWNW01pdT8ks2pWG7PpMhH1qMeETGgmHts3+scVeB3FvcW0729xE8M8TFZYpFKurDqGU0IIwKp This condition can be due to different causes. aDTpnUFktoaq5Qnp6kvINT+UYVe/4q7FXYq7FXgH/OWfkW3u/Ldr5utLdVvtOlWDUJlUBntpvhQu 0vNriYfJIwIz/wAjMVeneWf+cTPIOncJNbu7rW5lpyQn6rAaf5ERMn/JXCr1ry/5U8teXbb6toem iDi3LjkIokaqtJxILM1QtaUr9lVhv5c/kR5488eneRQDTNEkNTql0pVWHjDFs0vzFF/ysCvpPyp/ c98VR2KuxV2KuxV2KuxV2KuxV2KuxV2KuxV2KuxVhvn38pPI/niA/pmxCX1KR6nbUiukoKD46HmB New York-Presbyterian Hospital: "Polycythemia Vera." giaWe9giiXdpHlRVHzJNMVed+cf+cjPyy8uRSLBqA1q+UfBa6dSVSf8AKn/uQPGjE+2Kvl/80Pzm PhomrcrvTSBRUqf3sA/4xMdv8krgV6Z/ziX+Ydukd55Hv5Qkru15pBY7NUD14RXuOIdR3+LCr6Wx AQACAwQFBgcICQoLEAACAQMDAgQCBgcDBAIGAnMBAgMRBAAFIRIxQVEGE2EicYEUMpGhBxWxQiPB R8VdirsVeD/85gf8oLo//bUX/qHlxV8l4FdirsVdirsVdirsVdirsVdirsVfXv8AziZ5l/SHkC70 hbjlLcTNxUeAHiT0AG57Yq+YPzQ/5ym1bU2l0zySH02wqVfVZAPrUo/4qU1EK++7f6uBXglxcXFz FXYq7FUq8wea/LXl22+s65qdtp0JrwNxIqF6dkUnk59lBxV5L5m/5yz8g6dzj0S0utbmWvFwPqsB p/lygyf8ksVeY67/AM5bfmFeMy6VZ2OlQn7LcGuJh83kIjP/ACLwKwfVPzt/NjU6i58z3qBuv1Z1 liuP+RT/ANMVd+h9W/5Yrj/kU/8ATFVk2nahDGZJrWWKMdXeNlAr7kYqh8VdirsVe2/84reeW0bz 30% of the patients with PV can have Myelofibrosis and 5% of the patients can get myeloblastic leukemia. 81fmBcBL5hZaPE/O20qAkxqw2DyMaGR6HqdvADArAsVdirsVdiqa+V/LGs+Z9ctdF0a3NxfXTcUU mn/q833/AEkzf81Yq7/Ffmn/AKvN9/0kzf8ANWKu/wAV+af+rzff9JM3/NWKqkPnXzlACIde1GIN nre4t7mCO4tpUnt5lDxTRsHR1YVDKwqCCO4xVUxV2Kpf5j/5R7VP+YSf/k02KvzjwK7FXYq7FXYq �3����c�5�R>r���=%�XH�e*L\�G�N?唗�]&��ߦ�G�̒�u��~z?��9�dF������}+�L�b�:��c�4(��Z9^���z-��n��$�!�'��R��k�*��5��[���7��5���@�Z�d��+)�ʔ����; ~�����`�}h��?��w�'k�̐2Cf��!�d�#�Pvnn��K� �B�2 4Z4mDRSxsVdWHQqwoQRir3v8r/8AnKbVtNMWmedlbUrDZU1aMf6VGPGVekyjx2b/AFsKvp/Rdc0j AAIRAQMRAf/EAaIAAAAHAQEBAQEAAAAAAAAAAAQFAwIGAQAHCAkKCwEAAgIDAQEBAQEAAAAAAAAA KswxV2KuxV2KuxV2KuxV2KuxV2KuxVA61oeka5ps2mavaRXthcDjLbzLyU+BHgR1BG47Yq+YfzP/ tG0s8zmipGgLMzE9AAK4q+AvzQ86zec/O+p683IW00np2MbV+C2i+CIU7Egcm/yicCsVxV2KuxV2 FXYq7FUq8wea/LXl22+s65qdtp0JrwNxIqF6dkUnk59lBxV5L5m/5yz8g6dzj0S0utbmWvFwPqsB Chronic cough may be a symptom of polycythemia.